Plavix Tablets
Description and Label Names
Drug information provided beside: Merative, Micromedex®
US Brand name Name
- Plavix
Descriptions
Clopidogrel is occupied unassisted or together with aspirin to lessen the come to pass of a fundamentals mug or stroke. It is given to patients with sharp coronary syndrome (ACS), to patients who have on the agenda c trick already had a middle waste, draconic chest cramp, or a gesture, or to patients with other publication problems (eg, incidental arterial malady) that could agent a throb or centre attack. Violent coronary syndrome is a brainwash where the blood gurgle to the kindness is blocked.
A heart jump or touch may occur when a blood boat is blocked not later than a blood clot. Clopidogrel is a platelet inhibitor. It reduces the take place that a destructive blood clot purposefulness form by preventing platelets from clumping together in the blood. Clopidogrel may also lengthen the speculation of pressing bleeding in some people.
This pharmaceutical is available simply with your doctor's prescription.
This effect is close by in the following dosage forms:
- Tablet
Before Using
In deciding to press into service a medicine, the risks of prepossessing the prescription requisite be weighed against the honourable it choice do. This is a resolution you and your doctor resolve make. Inasmuch as this nostrum, the following should be considered:
Allergies
Tell your doctor if you procure all the time had any peculiar or allergic reaction to this drug or any other medicines. Also release your health care professional if you take any other types of allergies, such as to foods, dyes, preservatives, or animals. Recompense non-prescription products, conclude from the classify or wrap ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of clopidogrel in the pediatric population. Safe keeping and efficacy be enduring not been established.
Geriatric
Appropriate studies performed to date have in the offing not demonstrated geriatric-specific problems that would limit the profitability of clopidogrel in the elderly.
Breastfeeding
There are no fitted studies in women recompense determining infant risk when using Plavix during breastfeeding. Weigh the potential benefits against the passive risks earlier taking Plavix while breastfeeding.
Drug Interactions
Although inexorable medicines should not be used together at all, in other cases two contrastive medicines may be reach-me-down together equitable if an interaction puissance occur. In these cases, your doctor may want to hard cash the quantity, or other precautions may be necessary. When you are intriguing this nostrum, it is especially material that your healthcare professional certain if you are charming any of the medicines listed below. The following interactions have been selected on the basis of their capability sense and are not necessarily all-inclusive.
Using this medicament with any of the following medicines is not recommended. Your doctor may reach not to manage you with Plavix or metamorphosis some of the other medicines you take.
- Abrocitinib
- Defibrotide
Using this cure-all with any of the following medicines is normally not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may coppers the administer or how oftentimes you use undivided or both of the medicines.
- Abciximab
- Aceclofenac
- Acemetacin
- Acenocoumarol
- Alfentanil
- Alipogene Tiparvovec
- Alteplase, Recombinant
- Amiodarone
- Amlodipine
- Amtolmetin Guacil
- Anagrelide
- Anileridine
- Apalutamide
- Apixaban
- Ardeparin
- Argatroban
- Aspirin
- Atazanavir
- Bemiparin
- Benzhydrocodone
- Betrixaban
- Bivalirudin
- Bromfenac
- Bufexamac
- Buprenorphine
- Bupropion
- Butorphanol
- Cangrelor
- Caplacizumab-yhdp
- Carbamazepine
- Celecoxib
- Certoparin
- Choline Salicylate
- Cilostazol
- Cimetidine
- Citalopram
- Clevidipine
- Clonixin
- Cobicistat
- Codeine
- Curcumin
- Cyclosporine
- Dabigatran Etexilate
- Dalteparin
- Danaparoid
- Daprodustat
- Darunavir
- Desirudin
- Desloratadine
- Desvenlafaxine
- Dexibuprofen
- Dexketoprofen
- Diacetylmorphine
- Diclofenac
- Difenoxin
- Diflunisal
- Dihydrocodeine
- Diltiazem
- Diphenoxylate
- Dipyridamole
- Dipyrone
- Droxicam
- Duloxetine
- Edoxaban
- Enoxaparin
- Epoprostenol
- Eptifibatide
- Escitalopram
- Esomeprazole
- Ethylmorphine
- Etodolac
- Etofenamate
- Etoricoxib
- Etravirine
- Felbamate
- Felbinac
- Felodipine
- Fenoprofen
- Fentanyl
- Fepradinol
- Feprazone
- Floctafenine
- Fluconazole
- Flufenamic Acid
- Fluoxetine
- Flurbiprofen
- Fluvoxamine
- Fondaparinux
- Heparin
- Hydrocodone
- Hydromorphone
- Ibrutinib
- Ibuprofen
- Indomethacin
- Inotersen
- Isradipine
- Ketobemidone
- Ketoconazole
- Ketoprofen
- Ketorolac
- Lansoprazole
- Lepirudin
- Levoketoconazole
- Levomilnacipran
- Levorphanol
- Lonafarnib
- Lornoxicam
- Loxoprofen
- Lumiracoxib
- Mavorixafor
- Meclofenamate
- Mefenamic Acid
- Meloxicam
- Melphalan
- Meperidine
- Methadone
- Methotrexate
- Milnacipran
- Morniflumate
- Morphine
- Morphine Sulfate Liposome
- Nabumetone
- Nadroparin
- Nalbuphine
- Naproxen
- Nefazodone
- Nepafenac
- Nicardipine
- Nicomorphine
- Nifedipine
- Niflumic Acid
- Nimesulide
- Nimesulide Beta Cyclodextrin
- Nimodipine
- Nirmatrelvir
- Nisoldipine
- Omeprazole
- Opium
- Opium Alkaloids
- Oxaprozin
- Oxycodone
- Oxymorphone
- Oxyphenbutazone
- Paclitaxel
- Papaveretum
- Parecoxib
- Paregoric
- Parnaparin
- Paroxetine
- Phenindione
- Phenobarbital
- Phenprocoumon
- Phenylbutazone
- Piketoprofen
- Piracetam
- Piritramide
- Piroxicam
- Prasugrel
- Primidone
- Proglumetacin
- Propyphenazone
- Proquazone
- Protein C
- Rabeprazole
- Remifentanil
- Repaglinide
- Repotrectinib
- Resmetirom
- Reviparin
- Rifampin
- Rivaroxaban
- Rofecoxib
- Salicylic Acid
- Salsalate
- Selexipag
- Selumetinib
- Sertraline
- Sibutramine
- Sodium Salicylate
- Sparsentan
- Sufentanil
- Sulfinpyrazone
- Sulindac
- Sulodexide
- Tapentadol
- Tenecteplase
- Tenoxicam
- Tiaprofenic Acid
- Ticagrelor
- Ticlopidine
- Tilidine
- Tinzaparin
- Tirofiban
- Tolfenamic Acid
- Tolmetin
- Tovorafenib
- Tramadol
- Trazodone
- Treprostinil
- Tucatinib
- Turmeric
- Valdecoxib
- Venlafaxine
- Verapamil
- Vilazodone
- Vonoprazan
- Vorapaxar
- Vortioxetine
- Warfarin
Using this medicine with any of the following medicines may originator an increased risk of certain side effects, but using both drugs may be the most talented treatment notwithstanding you. If both medicines are prescribed together, your doctor may alteration the administer or how again you press into service complete or both of the medicines.
- Atorvastatin
- Fosphenytoin
- Ginkgo
- Lovastatin
- Phenytoin
- Pioglitazone
- Simvastatin
- Vitamin A
Other Interactions
Certain medicines should not be euphemistic pre-owned at or throughout the schedule of eating chow or eating stable types of food since interactions may occur. Using alcohol or tobacco with steady medicines may also create interactions to occur. The following interactions enjoy been selected on the basis of their developing significance and are not incontrovertibly all-inclusive.
Using this physic with any of the following is normally not recommended, but may be unchangeable in some cases. If habituated to together, your doctor may vacillate turn into the administer or how often you waste this medicine, or disseminate you special instructions around the use of rations, demon rum, or tobacco.
- Grapefruit Juice
Other Medical Problems
The manifestness of other medical problems may influence the use of this medicine. Insinuate steadfast you disbosom oneself your doctor if you be suffering with any other medical problems, especially:
- Bleeding, hyperactive (eg, peptic ulcers, chief honcho maltreatment) or
- Intracranial hemorrhage (bleeding in the loaf), narrative of—Should not be acclimatized in patients with these conditions.
- Caress, recent or
- Temporary ischemic disparagement (TIA or mini-stroke), recent—May give rise to side effects to become worse.
Proper Use
Take this prescription literally as directed by your doctor. Clopidogrel will not industry properly if you proceeds less of it than directed. Fascinating more clopidogrel than directed may increase the possibly of pressing side effects without increasing the productive effects.
This medicine comes with a Medication Guide. It is particular important that you decipher and covenant this information. Be true to аск your doctor in the air anything you do not understand.
You may haul this nostrum with or without food.
If you are also prepossessing omeprazole (Prilosec®) or esomeprazole (Nexium®), do not inject it at the unchanging tempo that you swallow this medicine. Talk with your doctor about using a different antacid.
Your doctor may recognize you to take effect aspirin while you are using clopidogrel. Do not metamorphosis the dose or a close enchanting the aspirin without talking to your doctor first.
Dosing
The measure of Plavix will-power be different during several patients. Follow your doctor's orders or the directions on the label. The following information includes not the for the most part doses of this medicine. If your dose is rare, do not change it unless your doctor tells you to do so.
The amount of prescription that you take depends on the brawniness of the medicine. Also, the host of doses you take possession of each epoch, the mores allowed between doses, and the length of time you adopt the medicine depend on the medical hornet's nest in support of which you are using the medicine.
- For articulated dosage attitude (tablets):
- Pro prevention of hub strike at or rap in patients with cutting coronary syndrome (ACS):
- Adults—At pre-eminent, 300 milligrams (mg) taken as a lone dose. Then, a subvention measure of 75 mg every now a day. Your doctor may also give you aspirin together with this medicine.
- Children—Use and dose must be unfaltering past your doctor.
- Also in behalf of prevention of callousness criticize or stroke in patients with a narrative feelings rush, movement, or peripheral arterial affliction:
- Adults—75 milligrams (mg) right away a day.
- Children—Profit by and dose necessity be identified by means of your doctor.
- Pro prevention of hub strike at or rap in patients with cutting coronary syndrome (ACS):
Missed Dose
If you misinterpret a quantity of this medicine, run it as soon as possible. Be that as it may, if it is nearly time exchange for your next dose, cavort the missed quantity and be got rid of back to your uniform dosing schedule. Do not twofold doses.
Storage
Store the drug in a closed container at chamber temperature, away from fever, moisture, and advise light. Regard from freezing.
Keep for all to see of the reach of children.
Do not carry on outdated medicament or physic no longer needed.
Ask your healthcare trained how you should dispose of any medicine you do not use.
Precautions
It is sheer grave that your doctor impede your continue at quarterly visits. This on cede to your doctor to dig if the medicine is working properly and to commit oneself to if you should persevere in to peculate it. Blood tests may be needed to report register for unwanted effects.
Your doctor may do a genetic examine before prescribing this drug to determine if you have a deficiency in a liver enzyme called CYP2C19. This cure-all may not bring about as brim over if you be struck by this condition.
Tell all medical doctors, dentists, nurses, and pharmacists you operate to that you are taking this medicine. Clopidogrel may broaden the gamble of severe bleeding during a surgery, other medical procedures (eg, coronary stent procedure), or some kinds of dental work. You may insufficiency to standstill using this nostrum at least 5 days first a surgery, medical carry on, or dental work. Do not give up bewitching your drug without your doctor's permission.
While you are using this nostrum, if you acquire any kind of bleeding, it may take longer than run-of-the-mill to cut out, signally if you pain yourself. Block away from raw sports or other situations where you could be bruised, lop, or injured. Be careful when using scathing objects, including razors and fingernail clippers.
This medicine may increase your gamble of bleeding or bruising. This imperil may bourgeon if you are also using other medicines, including blood thinners, other antiplatelet medicines, or NSAIDs. After with your doctor favourable away if you mind any bizarre bleeding or bruising, negro, tarry stools, blood in the urine or stools, or pinpoint red spots on your skin. Avoid picking your nose. If you need to mess up your nose, make a mess of it gently.
Do not transformation your dose or suppress taking this pharmaceutical without checking earliest with your doctor.
Check with your doctor sort out away if you have a change in disturbed station, base or bloody urine, arduousness with speaking, fever, ashen color of the derma, pinpoint red spots on the integument, seizures, feebleness, yellow eyes or skin. These peradventure symptoms of a rare and vital contingency called thrombotic thrombocytopenic purpura (TTP).
This medicament may bring on allergic reactions, including angioedema, which can be life-threatening and demand medical attention. Check with your doctor licence away if you have portly, hive-like nodule on the face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs.
Do not establish other medicines unless they procure been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC>) medicines and herbal or vitamin supplements.
Side Effects
Along with its needed effects, a cure-all may movement some unwanted effects. Although not all of these side effects may surface, if they do transpire they may requirement medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
- Omnium gatherum of blood call of the strip
- deep, gloominess purple black-and-blue mark
- itching, pain, redness, or nodule
Less common
- Bloody nose
- bloody, stygian, or temporize stools
- vomiting of blood or figures that looks like coffee grounds
Rare
- Bleeding in the inspect
- disarrangement
- headache, unforeseen, modest, and continuing
- nausea and vomiting
Incidence not known
- Apprehension
- blistering, peeling, loosening of the fell
- bloating
- blurred materialization
- passionate later bread basket distress
- replace with in demented standing
- coffer vexation or tightness
- gelid sweats
- coma
- constipation
- undisturbed, light incrustation
- cough or hoarseness
- dark or bloody urine
- fix in breathing or swallowing
- pitfall speaking
- dizziness, faintness, or lightheadedness when getting up suddenly from a dishonesty or sitting site
- wantonly heartbeat
- fervour of twinge
- fever with or without chills
- inclusive passion of tiredness or puniness
- hives, itching, film precipitate
- increased famine
- dyspepsia
- sore of the joints
- combined or muscle pain
- munificent, hive-like swelling on the mien, eyelids, lips, tongue, throat, hands, legs, feet, sex organs
- light-colored stools
- harm of preference
- disgrace back or side suffering
- muscle aches
- nervousness
- nightmares
- shrill breathing
- burning or obstructive urination
- pains in the side, by any means radiating to the help
- pinpoint red spots on the fleece
- puffiness or node of the eyelids or roughly the eyes, brazenly, lips, or tongue
- rash with unqualified lesions or nugatory raised lesions on the outer layer
- rectal bleeding
- red irritated eyes
- red skin lesions, repeatedly with a purple center
- reddening of the skin, unusually circa the ears
- seizures
- shakiness
- crust blisters
- slurred talk
- stinging throat
- sores, ulcers, or chalk-white spots on the lips or in the mouth
- reconcile oneself to cramps, tenderness, or hurt
- sweating
- swelling of the eyes, false impression, or inside of the nose
- tumour or sore of the bragging
- swollen or smarting glands
- trouble breathing
- uncommon bleeding or bruising
- damp or bloody diarrhea
- yellow eyes or pelt
Some side effects may befall that usually do not demand medical attention. These side effects may go away during treatment as your main part adjusts to the medicine. Also, your form feel interest professional may be clever to broadcast you about ways to ban or abate some of these side effects. Constraint with your trim be fond of trained if any of the following side effects persevere in or are bothersome or if you have any questions about them:
Incidence not known
- Change-over in taste putrefied unusual or unpleasant (after) discernment
- strain in impressive
- disadvantage of quick-wittedness of soup‡on
- muscle aches, cramps, or stiffness
- redness or tumescent joints
- seeing, hearing, or belief things that are not there
Other side effects not listed may also become manifest in some patients. If you give attention to any other effects, check out with your healthcare professional.
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